Week 1 · Tue, Nov 10 · 1:15 AM ET

Buffalo Bills vs Minnesota Vikings: prediction & pick

Minnesota Vikings host Buffalo Bills in a matchup where the model sides with Buffalo Bills. Our projection has BUF favored by roughly 1.5 points, a win probability near 55%, and a projected final of BUF 24 – MIN 22.

Against the spread

Where the book sits at 3 on MIN, our simulation disagrees by enough to make this a live spread play. The recommendation is MIN +3, an edge of about 1.5 points in our favor.

Total (over/under)

On the total, the model projects around 45.5 combined points versus a market number of 48.5. That points to the Under 48.5, with about 3.0 points of under edge.

The projection

Running the matchup through the model produces a projected final score of BUF 24 – MIN 22, built from each team's power rating, home-field advantage, and pace. See how the model works for the full methodology.

Betting involves risk. Lines move — always confirm the current number at your sportsbook before betting. 21+ where legal.

Bottom line: the model rates this a Strong play at 68% confidence. As always, shop for the best available number and size the bet to your bankroll — a single game never makes or breaks a season.