Week 1 · Tue, Oct 13 · 12:15 AM ET

Buffalo Bills vs Los Angeles Rams: prediction & pick

Los Angeles Rams host Buffalo Bills in a matchup where the model sides with Buffalo Bills. Our projection has BUF favored by roughly 1.0 points, a win probability near 53%, and a projected final of BUF 24 – LAR 23.

Against the spread

Where the book sits at -3 on LAR, our simulation disagrees by enough to make this a live spread play. The recommendation is BUF +3, an edge of about 4.0 points in our favor.

Total (over/under)

On the total, the model projects around 47.0 combined points versus a market number of 53.5. That points to the Under 53.5, with about 6.5 points of under edge.

The projection

Running the matchup through the model produces a projected final score of BUF 24 – LAR 23, built from each team's power rating, home-field advantage, and pace. See how the model works for the full methodology.

Betting involves risk. Lines move — always confirm the current number at your sportsbook before betting. 21+ where legal.

Bottom line: the model rates this a Strong play at 88% confidence. As always, shop for the best available number and size the bet to your bankroll — a single game never makes or breaks a season.